NOVOS Core
NOVOS Core
The first formula targeting all 12 biological Hallmarks of Aging. Backed by over 7 years of R&D and randomized, placebo-controlled human trials, it delivers positive outcomes on cardiovascular and general aging functional markers.
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NOVOS Core
DESCRIPTION
DESCRIPTION
NOVOS Core is the first formulation designed around all 12 biological Hallmarks of Aging, developed with leading longevity scientists and physicians specializing in aging biology.
Backed by more than seven years of R&D, it has been evaluated in randomized, double-blind, placebo-controlled human clinical research demonstrating statistically significant effects across validated measures of endothelial function, arterial flexibility, and systolic blood pressure in the normal range, with effect sizes among the largest reported in published human research for a supplement, nutritional, or lifestyle intervention.
Built as a coordinated, multi-pathway system rather than a single-ingredient solution, NOVOS Core is designed to support multiple aging-related systems at once. In addition to cardiovascular outcomes, research has observed favorable shifts in biological age markers measured epigenetically and improvements in skin firmness in preliminary human studies, alongside customer-reported benefits such as steadier energy, mental clarity, mood balance, and sleep consistency. The formulation is further supported by mechanistic studies and preclinical lifespan research, providing multi-level scientific evidence that NOVOS Core supports foundational aspects of healthy aging biology.
†Customer-reported outcomes and small scale studies. Individual results will vary.
HOW IT WORKS
HOW IT WORKS
A system designed to support the biology of aging itself
Aging doesn’t happen in one place. It emerges from interconnected biological processes that influence cardiovascular function, cellular energy production, tissue renewal, and resilience across the body.
NOVOS Core was intentionally designed around the biology of aging itself — not individual symptoms — by supporting all 12 biological Hallmarks of Aging simultaneously. Developed with scientists and physicians affiliated with institutions including Harvard Medical School, MIT, and the Salk Institute, the formulation is built as a coordinated system designed for ingredient synergy rather than a collection of isolated or trendy ingredients.
Because these foundational systems shape how the body functions day to day, supporting them can influence performance, resilience, and overall well-being long before later-life outcomes become relevant.
Built on evidence, not theory
NOVOS Core is supported by multiple layers of research:
- Mechanistic studies to understand how it influences aging-related biological pathways
- Preclinical lifespan studies in mice, where animals receiving NOVOS Core lived over 18% longer on average (animal models do not predict human outcomes and are not indicative of impact on humans)
- Randomized, placebo-controlled human clinical research using validated functional biomarkers commonly applied in cardiovascular and aging science
This multi-level approach reflects an uncommon standard of scientific validation for a nutritional formulation — testing the complete system rather than relying on individual ingredient claims.
What the formulation is designed to support
Cellular energy & metabolic efficiency
Supports mitochondrial and metabolic pathways involved in cellular energy production to help maintain stamina, clarity, and daily recovery.
Healthy cellular renewal
Supports the body’s natural renewal and turnover processes that help maintain tissue function over time.
Cellular resilience & stability
Supports DNA stability, cellular stress-response pathways, and healthy inflammatory balance to promote long-term cellular function.
Protein quality & cellular communication
Supports proteostasis, extracellular matrix structure, and intercellular signaling — helping tissues remain coordinated and responsive with age.
Why this approach is different
Most supplements focus on isolated ingredients or single outcomes, while few are rigorously evaluated as complete formulations in randomized, placebo-controlled human clinical trials using validated functional biomarkers.
NOVOS Core was designed to support the biology of aging as a connected system and evaluated as a complete formulation through mechanistic research, preclinical lifespan studies, and human clinical trials — not trends, theories, or ingredient-by-ingredient claims.
Few dietary supplements are evaluated this way, testing the complete finished formula in humans rather than relying on ingredient-level assumptions.
These statements have not been evaluated by the Food and Drug Administration. This product/information is not intended to diagnose, treat, cure, or prevent any disease.
INGREDIENTS
INGREDIENTS
Each ingredient in NOVOS Core was selected based on scientific evidence and is either naturally present in human biology or derived from compounds found in nature. Together, they were chosen for their roles in aging-related biological pathways and for their established safety profiles in human research.
1. Calcium Alpha-Ketoglutarate (Ca-AKG) - A compound naturally present in human metabolism that supports mitochondrial energy production and cellular resilience.
2. Fisetin - A polyphenol found in strawberries and other fruits that supports cellular renewal and healthy inflammatory balance.
3. Pterostilbene - An antioxidant compound found in blueberries that supports cardiovascular and metabolic health.
4. Glucosamine Sulfate – Naturally occurring in connective tissues, supports joint and extracellular matrix integrity.
5. Glycine – An amino acid abundant in collagen that supports recovery, detoxification, and restorative sleep.
6. Magnesium Malate – A form of magnesium involved in ATP production that supports energy metabolism and muscle function.
7. L-Theanine – An amino acid found in green tea that supports calm focus and stress resilience.
8. Rhodiola Rosea – An adaptogenic root traditionally used to support stamina, mental performance, and stress response.
9. Gingerols & Shogaols – Bioactive compounds from ginger that support healthy inflammatory signaling and digestive comfort.
10. Hyaluronic Acid – A molecule naturally present in skin and joints that supports hydration, elasticity, and tissue resilience.
11. Vitamin C – An essential nutrient found in fruits and vegetables that supports collagen production, antioxidant protection, and synergizes with CaAKG.
12. Micro-dosed Lithium – A trace mineral found naturally in water and foods that supports neuronal signaling and mood balance.
These statements have not been evaluated by the Food and Drug Administration. This product/information is not intended to diagnose, treat, cure, or prevent any disease.
CLINICAL TRIAL & SCIENTIFIC EVIDENCE
CLINICAL TRIAL & SCIENTIFIC EVIDENCE
Placebo-Controlled Human Clinical Trial Cardiovascular function was selected as the first human system to measure because vascular biology changes early with age and reflects whole-body resilience.
NOVOS Core was evaluated in a randomized, double-blind, placebo-controlled human clinical trial conducted by university researchers in adults aged 40+. The study assessed validated functional biomarkers commonly used in cardiovascular and aging research.
Compared with placebo, NOVOS Core demonstrated statistically significant differences across multiple measures of cardiovascular function:
- +3.4% improvement in endothelial function (Flow-Mediated Dilation, FMD) observed shortly after the first dose and sustained over six months
- −1.18 m/s difference in arterial stiffness (Pulse Wave Velocity) at six months
- −8.5 mmHg difference in systolic blood pressure, supporting healthy levels already within the normal range
Effect sizes across these independent cardiovascular biomarkers are among the largest reported in published human research for a nutritional intervention, supplement, or lifestyle modification, including aerobic exercise, providing rare human evidence that a multi-pathway formulation can measurably influence aging-related physiology.
Individual responses vary. Not every person will experience the same magnitude of change.
Real People. Real Routines. Aging, Done Differently.
Biotechnology rigor. 7+ years of R&D. A higher standard for longevity.
The Science That Puts Core in a Class of Its Own
Supported by over 7 years of research,400+ ingredient studies, and a rapidly expanding body of clinical and preclinical evidence.
CLINICALLY OBSERVED SHIFTS IN VASCULAR AGING MARKERS
What they did: Independent university investigators conducted a randomized, double-blind, placebo-controlled human clinical trial in adults 40+, evaluating NOVOS Core as a complete formulation over six months using validated vascular biomarkers.
What they found: Compared with placebo, NOVOS Core
showed statistically significant improvements in:
●endothelial function (+3.4% FMD)
●arterial flexibility(-118 m/s PWV)
● systolic blood pressure(-8.5 mmHg)
Effect sizes were larger than those typically reported for
commonly studied supplements and lifestyle approaches,
including beetroot/nitrates,cocoa flavanols,omega-3s,DASH-
style diets, and aerobic or HllT exercise.
Why that matters: Randomized human trials demonstrating
measurable changes across multiple aging-related systems are
exceptionally rare in the supplement category, providing first-
of-its-kind human evidence of simultaneous,positive effects
on endothelial function, arterial flexibility, and healthy blood
pressure already within the normal range from a single,multi-
component nutritional intervention.
MOUSE LIFESPAN STUDY
What they did: Researchers evaluated NOVOS Core in a controlled preclinical mouse model across the full adult lifespan.
What they found: Mice receiving NOVOS Core lived over 18% longer on average than controls 一a magnitude of effect uncommon for multi-ingredient formulations and more typically associated with interventions studied in aging biology research.
Why that matters: Lifespan studies in animals are a foundational step in aging science for assessing whole-body biological effects. While results in animal models do not necessarily predict human outcomes,these findings,alongside mechanistic and human clinical research, provide additional evidence of system-level biological activity in vivo.
EPIGENETIC AGING ASSESSMENT
What was done: A group of first-time NOVOS Core customers completed DNA methylation-based epigenetic age testing through an independent third-party laboratory before and after six months of use, while maintaining their usual diet and lifestyle.
What was observed: Follow-up testing showed favorable directional shifts in validated epigenetic aging biomarkers, including DunedinPACE,corresponding on average to approximately one month per year in a slower pace of biological aging across the group.
Why that matters: Epigenetic clocks are widely used research tools that estimate biological aging by analyzing DNA methylation patterns. While these observational results are exploratory and not diagnostic or predictive of individual outcomes,they provide additional real-world data on how NOVOS Core may support aging-related biology over time.
SKIN HEALTH & FIRMNESS EVALUATION
What they did: In a small preliminary pilot evaluation, individuals took NOVOS Core daily for six months. Skin firmness and elasticity were measured using an indentometer, an objective device commonly used to assess skin mechanical properties.
What they found: Indentometer measurements showed increases in skin firmness ranging from 12% to 40%,with an average improvement of 22% across the group.
Why that matters: Indentometer testing provides quantifiable insight into structural skin properties over time. While preliminary,these results suggest that supporting foundational biological pathways may also help maintain skin firmness and resilience.
REDUCTION IN DNA STRAND BREAKS FROM CHEMICAL STRESSORS
What they did: University of Bologna researchers evaluated NOVOS Core in a controlled 3D human skin-cell model exposed to chemical stress,measuring laboratory markers associated with DNA damage and oxidative stress.
What they found: Cells pre-treated with NOVOS showed lower laboratory signals associated with DNA strand breaks and oxidative stress compared with untreated stressed cells.
Why that matters: DNA integrity and oxidative stress response are fundamental processes studied in aging biology. These laboratory findings provide mechanistic evidence of cellular resilience,but do not represent effects in humans.
INFLAMMATION SIGNAL MODULATION
What they did: Researchers at the Salk Institute for Biological Studies evaluated NOVOS Core ingredient combinations in controlled neuronal and microglial cell models,measuring laboratory markers associated with cellular stress and inflammatory signaling.
What they found: The combined formulation demonstrated stronger activity than individual ingredients and favorably reduced nitric oxide output in activated microglial cells—a common laboratory readout used to assess inflammatory signaling in vitro.
Why that matters: Cellular stress and inflammatory signaling pathways are widely studied in aging biology. These laboratory findings provide mechanistic support for how coordinated ingredient combinations may influence cellular resilience, but do not represent human outcomes.
SENESCENT CELL SUPPORT
What they did: Researchers at Newcastle University tested NOVOS Core ingredient combinations in human cells grown in the lab that displayed characteristics of cellular senescence- a state where older, stressed cells stop functioning optimally and cause inflammation.
What they found: The combined formulation showed positive effects on senescent cells, reducing their size by approximately 50%,while healthy, non senescent cells were not measurably affected.
Why that matters: Cellular senescence is one of the recognized hallmarks of aging. These laboratory findings help explain how coordinated ingredients may support cellular resilience, but they do not represent effects in humans.
REDUCTION IN DNA OXIDATIVE DAMAGE
What they did: An independent laboratory evaluated NOVOS Core ingredient combinations in human endothelial cells exposed to irradiation, measuring 8-OHdG 一a widely used laboratory marker measuring oxidative DNA damage.
What they found: Cells pre-treated with the NOVOS Core formulation showed substantially lower 8-OHdG levels across multiple doses, with laboratory markers up to 77% lower (68% lower on average) compared with untreated stressed cells.
Why that matters: DNA integrity and oxidative stress responses are fundamental processes studied in aging biology. These laboratory findings provide mechanistic insight into cellular resilience under stress,but do not represent effects in humans.
Human Clinical Trial Results
In a randomized, double-blind, placebo-controlled human clinical trial, NOVOS Core demonstrated statistically significant improvements versus placebo across validated cardiovascular biomarkers used in aging research.
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Endothelial Function (Circulation)
NOVOS Core supported healthy endothelial responsiveness with sustained effects measuring approximately 1.26x to 4.65x of leading studied supplements, outperforming tea polyphenols, cocoa flavanols,beetroot nitrates, and demonstrating effects comparable to those reported for weight loss, aerobic exercise, and resistance training.
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Arterial Flexibility (Blood Vessels)
NOVOS Core helped support healthy arterial flexibility with effect sizes exceeding those reported for magnesium and omega-3s,and comparable to published results for weight loss, DASH heart health diets, and structured exercise 一 an effect rarely observed with dietary supplements.
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Systolic Blood Pressure Support
Supported ~8.5-8.7 mmHg differences in systolic blood pressure vs. placebo in adults already in the normal range, exceeding effect sizes reported for common supplements including beetroot/nitrate and potassium, and demonstrating magnitudes of support comparable to those observed for Mediterranean and DASH-style diets and High Intensity Interval Training (HllT).
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
The first to design a formulation to address all 12 biological hallmarks of aging , years ahead of the field.
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Cellular Cleanup & Quality Control
1. Cellular senescence balance
2. Protein quality control (proteostasis)
3. Autophagy & cellular recydling -
Energy & Metabolic Function
4. Mitochondrial energy production
5. Nutrient sensing pathways
6. Gut microbiome balance -
Genomic & Epigenetic Stability
7. DNA integrity & maintenance
8. Epigenetic regulation
9. Stem cell health & renewal potential -
Inflammation & Tissue Communication
10. Healthy inflammatory balance
11. Intercellular communication
12. Extracellular matrix & tissue structure
What You'll Actually Feel & What's Happening
When you support the fundamental drivers of aging, you optimize how your cells function — and how you look and feel today and for years to come.
Clinically Studied in a Placebo-Controlled
Human Trial
Benefits
●Support vascular resilience and
flexibility
●Help maintain healthy blood flow and
blood pressure already within the
normal range
●Clinically demonstrated support for key
markers of vascular aging
Aging Pathways Supported
●Endothelial function
●Arterial elasticity
●Healthy blood pressure balance
●Cellular resilience & metabolic signaling
Based on customer-reported outcomes and human clinical
research of individual component ingredients of the formulation. This
statement has not been evaluated by the Food and Drug
Administration.This product is not intended to diagnose,treat,cure,
or prevent any disease.
Benefits
●More consistent, steady energy
throughout the day
●Supports stamina and physical capacity
●Many people notice changes within the
first few weeks,with continued benefits
over time
Aging Pathways Supported
●Mitochondrial energy production
●Nutrient sensing & metabolic efficiency
●Cellular repair and stress response
Based on customer-reported outcomes and human clinical
research of individual component ingredients of the formulation. This
statement has not been evaluated by the Food and Drug
Administration.This product is not intended to diagnose,treat,cure,
or prevent any disease.
Benefits
●Supports focus and clear thinking
●Helps maintain memory and cognitive
function
●Supports balanced mood and emotional
well-being
Aging Pathways Supported
●Healthy inflammatory balance
●Cellular communication & synaptic
function
●Cellular resilience & stress response
Based on customer-reported outcomes and human clinical
research of individual component ingredients of the formulation. This
statement has not been evaluated by the Food and Drug
Administration.This product is not intended to diagnose,treat,cure,
or prevent any disease.
Benefits
●Supports skin firmness, elasticity, and
resilience
●Helps improve the look and feel of skin
over time
●Many people notice visible changes
within weeks, with continued
improvements over months
Aging Pathways Supported
●Collagen structure & extracellular matrix
integrity
●Skin barrier function & hydration
balance
●Cellular energy & metabolic processes
Based on customer-reported outcomes and human clinical
research of individual component ingredients of the formulation. This
statement has not been evaluated by the Food and Drug
Administration.This product is not intended to diagnose,treat,cure,
or prevent any disease.
Benefits
●Supports long-term vitality and
performance as you age
●Coordinated support across multiple
biological systems
●One complete daily formula instead of
complex supplement stacks
Aging Pathways Supported
● Designed around all 12 biological
hallmarks of aging
●Cellular maintenance & resilience
●System-wide metabolic & signaling
balance
Based on customer-reported outcomes and human clinical
research of individual component ingredients of the formulation. This
statement has not been evaluated by the Food and Drug
Administration.This product is not intended to diagnose,treat,cure,
or prevent any disease.
Timeline of Change
Clinically observed biological shifts begin early and build with consistent daily use.
Grounded in human clinical research and supported by mechanistic, preclinical lifespan, and epigenetic studies.
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Day 1+
Within 2 hours: Clinical research observed early changes in vascular function biomarkers, including endothelial responsiveness and systolic blood pressure signaling.
Feel: Some users report subtle increases in mental clarity and drive after initial use.Cellular support: Ingredients begin engaging antioxidant and cellular stress response pathways that support system-level resilience.
-
Month 1+
Daily energy: More consistent energy as cellular energy pathways adapt to regular use.
Recovery & comfort: Users often report improved day-to-day physical comfort and easier recovery from activity.
Inflammatory balance: Supports healthy inflammatory signaling tied to resilience and repair. -
Months 6+
Heart & vessels: Randomized, placebo-controlled human research demonstrated statistically significant differences in vascular aging biomarkers, including arterial flexibility (PWV) and support for healthy blood pressure already within the normal range.
Skin appearance: In a pilot human assessment using objective instrument measurements, participants showed measurable improvements in skin firmness and elasticity over six months, consistent with healthier-looking, more resilient skin.
System-wide longevity support: Ongoing use supports multiple core biological pathways associated with healthy aging through a coordinated,multi-system approach.
Pace of aging: In epigenetic research testing, participants showed directional changes consistent with a slower pace of biological aging over time.Epigenetic analyses are research tools and do not diagnose disease or predict lifespan.
60-Second Ritual with Compounding Longevity Benefits
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One sachet daily.
Designed for once-a-day simplicity
Take with or after a meal.
Gentle on the stomach, easy to remember
Mix into water, a smoothie, or yogurt.
Dissolves easily. No pills. No stacking.
Inventing the Future of Longevity
12 Longevity Ingredients. 1 Clinical-Strength Formula.
The Most Effective Longevity Drink On The Market
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Calcium Alpha-Ketoglutarate (Ca-AKG)
A naturally occurring metabolic intermediate involved in mitochondrial energy production. Studied for cellular protection, metabolic health, and epigenetic support, with lifespan and healthspan benefits demonstrated in animals
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Fisetin
A plant polyphenol studied in aging research for its role in supporting cellular senescence balance and healthy inflammatory signaling. In animal models, fisetin has been associated with lifespan extension
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Glycine
An amino acid naturally present in collagen and metabolism. Higher glycine levels are associated with cardiovascular health, balanced inflammatory signaling, and healthy glucose metabolism. Lifespan benefits have been observed in multiple species
-
Pterostilbene
A compound found in blueberries with higher bioavailability than resveratrol. Supports healthy inflammatory balance, DNA stability, and epigenetic regulation. Related compounds have demonstrated lifespan effects in animal models
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Pterostilbene
An adaptogenic botanical containing salidroside and other bioactives studied for cellular stress resilience. Research suggests support for mitochondrial function, AMPK and sirtuin pathways, and healthy cellular aging processes
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Micro-dosed Lithium
Trace amounts of lithium naturally occur in food and water. Epidemiological and human studies associate low-dose lithium exposure with healthy brain aging and longevity trends. Lifespan effects have also been observed in multiple species
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Magnesium Malate
Magnesium supports hundreds of enzymatic reactions involved in energy production and metabolic health, while malate participates in the Krebs cycle. Together they support cellular energy and resilience
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Glucosamine Sulfate
Commonly known for joint health, glucosamine is also studied for its role in healthy inflammatory balance and metabolic pathways that resemble calorie-restriction biology. Lifespan associations have been observed in animals and population studies
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Hyaluronic Acid
A naturally occurring structural molecule that supports skin hydration and elasticity. Oral supplementation has been shown to improve skin appearance and texture over time
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L-Theanine
A green tea amino acid that promotes calm focus and healthy stress response. Studied for supporting antioxidant defenses and longevity-related cellular pathways in preclinical research
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Vitamin C
An essential antioxidant that supports collagen formation, cellular protection, and epigenetic enzyme activity. Works synergistically with other nutrients to maintain cellular integrity
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Ginger Extract (Gingerols)
Bioactive compounds from ginger that support healthy inflammatory balance, metabolic function, and cellular antioxidant defenses
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Clinically Studied Formulation
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3rd-Party Tested
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Sugar-Free & Gluten-Free
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Clinically Relevant Doses
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Vegan & Clean Label
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Developed by Scientists.
Formulated by a team of 7 scientists and physicians specializing in aging biology, with backgrounds at Harvard Medical School, MIT, and leading research institutions.
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Trusted by Doctors.
Recommended by more than 1,500 MDs and clinicians, including physicians affiliated with Mayo Clinic.
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Respected by the Press.
Featured by The Wall Street Journal as a longevity brand helping define the future of the field.
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Recognized by Awards.
Recipient of multiple consumer and industry awards for innovation in science-based longevity.
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Loved by our Community.
More than 10 million doses enjoyed worldwide by our growing global community.
Built and studied by world-class scientists and MD researchers dedicated to advancing the science of longevity and human healthspan.
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Dr. George Church, PhD
"I see NOvOS as inspiring 一 they approach aging as a complex phenomenon, aiming at all pathways and hallmarks of aging simultaneously."
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Dr. Satomi Miwa
"The study demonstrates that this multi ingredient formulation exhibits synergistic effects rarely achieved by a nutritional supplement."
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Dr. Pamela Maher, PhD
"What really impressed me about NOvOS was the comprehensiveness of their analysis of aging research to design their product."
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Dr. J. Pedro Magalhaes, PhD
"NOvOS has been using a novel science-based approach for developing its formulation. [They are] a leader in the longevity space."
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Dr. Robert Lufkin,MD
"It's the rigorously-researched, science-backed formulations that set NOvOS apart in the longevity supplements space."
Love & Repeat
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SAVE 19%NOVOS Core
Regular price $88.00Regular price $88.00 Sale priceUnit price per$109.0019% -
SAVE 13%NOVOS Boost
Regular price $38.00Regular price $38.00 Sale priceUnit price per$44.0013% -
SAVE 19%NOVOS Boost+Core
Regular price $123.00Regular price $123.00 Sale priceUnit price per$153.0019%
Questions, answered.
IS NOVOS CORE SAFE WITH MEDICATIONS?
IS NOVOS CORE SAFE WITH MEDICATIONS?
NOVOS Core is a dietary supplement, not a medication. If you take prescription medications or manage a medical condition, consult your healthcare professional before use, especially if you are pregnant or nursing, managing blood pressure, bleeding or clotting, or any chronic condition.
HOW IS NOVOS CORE DIFFERENT FROM YOUR OTHER PRODUCTS?
HOW IS NOVOS CORE DIFFERENT FROM YOUR OTHER PRODUCTS?
NOVOS Core is the daily foundation. It’s a comprehensive longevity formulation designed to support multiple aging-related biological pathways as a complete system.
Other NOVOS products are designed as targeted add-ons — for example, additional NAD+ or mitochondrial support — and can be layered on top of NOVOS Core depending on your goals.
HOW LONG UNTIL I NOTICE RESULTS?
HOW LONG UNTIL I NOTICE RESULTS?
Timelines vary by individual.
Some people report noticing day-to-day changes first, such as steadier energy or improved sleep consistency, within the first few weeks. Broader, longer-horizon changes associated with healthy aging biology typically build gradually over weeks to months and depend on baseline health and consistent use.
ARE THERE ANY AGE RELATED RESTRICTIONS?
ARE THERE ANY AGE RELATED RESTRICTIONS?
NOVOS Core is intended for adults. If you’re under 18, pregnant, or breastfeeding, consult a healthcare professional before use.
CAN I TAKE MORE THAN ONE SACHET PER DAY?
CAN I TAKE MORE THAN ONE SACHET PER DAY?
NOVOS Core is designed for one sachet daily. Some individuals choose to take up to two sachets per day. If increasing your intake, consider starting with one sachet for at least a week and consult your healthcare professional if you are sensitive to supplements.
HOW DO I KNOW IT’S WORKING?
HOW DO I KNOW IT’S WORKING?
There are two practical ways many people evaluate progress:
How you feel
Some people notice day-to-day changes such as steadier energy, sleep consistency, mood improvements, or overall resilience over time.
What you can measure
NOVOS Core is designed to support underlying biological systems associated with healthy aging, effects that may not always be immediately perceptible but can be observed through objective measures. In human clinical research, NOVOS Core demonstrated statistically significant benefits across validated functional biomarkers of cardiovascular function, including endothelial responsiveness, arterial flexibility, and support for healthy blood pressure already within the normal range.
If you already track general wellness metrics, you may choose to monitor markers such as resting heart rate, sleep patterns, blood pressure, or routine labs with your clinician.
Because these changes reflect foundational physiology, benefits are often gradual and cumulative rather than instant.
HOW DOES THE PRICE COMPARE TO ALTERNATIVES?
HOW DOES THE PRICE COMPARE TO ALTERNATIVES?
NOVOS Core replaces the need to source and dose multiple individual supplements. Instead of assembling a complex stack, you get a single, research-driven formulation developed and evaluated as a complete system. You’re investing in clinical research, quality controls, and formulation design — often at a comparable or lower total cost than buying similar ingredients separately.
WHAT IS NOVOS CORE MADE OF?
WHAT IS NOVOS CORE MADE OF?
NOVOS Core contains 12 research-backed longevity ingredients:
- Vitamin C
- Magnesium Malate
- Calcium Alpha-Ketoglutarate
- Glycine
- Glucosamine Sulfate
- Rhodiola
- L-Theanine
- Hyaluronic Acid
- Fisetin
- Gingerol
- Pterostilbene
- Micro-dosed Lithium
The Orange flavor also includes erythritol, malic acid, stevia, and natural flavors. Core is vegan, non-GMO, sugar-free, and free from artificial colors and preservatives.
WHO IS NOVOS CORE FOR?
WHO IS NOVOS CORE FOR?
NOVOS Core is designed for adults of all ages who want to proactively support healthy aging.
- Younger users benefit from early support, while older adults may notice more immediate short-term effects.
IS NOVOS CORE COMPATIBLE WITH MY DIET OR DIETARY RESTRICTIONS?
IS NOVOS CORE COMPATIBLE WITH MY DIET OR DIETARY RESTRICTIONS?
NOVOS Core is free from:
- Dairy, gluten, soy, nuts, and shellfish
- Sugar, calories, and GMOs
- Preservatives and 14 EFSA-listed allergens
It suits vegan, vegetarian, Mediterranean, keto, gluten-free.
ARE THERE ANY SIDE EFFECTS?
ARE THERE ANY SIDE EFFECTS?
A small percentage of users experience temporary stomach discomfort when starting Core. Taking it with food, splitting the dose, or mixing it with extra water typically resolves this within a few weeks.
CAN I TAKE NOVOS CORE WHILE PREGNANT OR BREASTFEEDING?
CAN I TAKE NOVOS CORE WHILE PREGNANT OR BREASTFEEDING?
NOVOS recommends avoiding Core during pregnancy and breastfeeding as a precaution.
DOES NOVOS CORE NEED REFRIGERATION?
DOES NOVOS CORE NEED REFRIGERATION?
No. Store Core at room temperature in a cool, dry place.